Some of the hardships faced by Hollywood actors are the constant parties and events that everyone who is somebody has to make an effort to attend. At these parties, it is guaranteed there will never be a shortage of food and alcohol.
Vince Vaughn is perhaps a willing participant at these events as he attained more success in his acting career. Over the years Vince Vaughn has gained weight and aged rather quickly.
http://www.tvsquad.com/2005/12/15/what-the-hell-happened-to-vince-vaughn/